2000-2009年浙江省肿瘤登记地区前列腺癌发病和死亡分析

Analysis of incidence and mortality of prostate cancer in cancer registration area in Zhejiang province from 2000 to 2009

目的 研究浙江省肿瘤登记地区2000-2009年前列腺癌发病与死亡的流行状况及趋势. 方法 2000-2009年前列腺癌发病与死亡数据来源于浙江省6个肿瘤登记地区,为杭州市、嘉兴市、嘉善县、海宁市、上虞市和仙居县,并经浙江省癌症中心审核、整理和统计分析,计算粗率、标化率及变化趋势. 结果 2000-2009年浙江省肿瘤登记地区前列腺癌发病率为9.79/10万,世界标化发病率为6.39/10万,0～ 74岁累积率为0.72％;死亡率为2.73/10万,世界标化死亡率为1.74/10万,0～74岁累积率为0.14％.年龄别发病率50岁前发病率较低且波动,50岁之后随着年龄增加快速增长,而年龄别死亡率则在55岁之后快速增长,均在85岁以上达到高峰,为130.30/10万和81.19/10万.前列腺癌发病率从2000年的1.39/10万,升高到2009年的13.89/10万,年度变化百分比为14.18％ （95％ CI 9.68％ ～ 18.98％）.死亡率从2000年的1.52/10万,升高到2009年的3.58/10万,年度变化百分比为11.83％ （95％CI 5.96％ ～ 18.33％）. 结论 浙江省肿瘤登记地区2000-2009年前列腺癌发病率和死亡率呈持续快速增长趋势,应加强前列腺癌防治工作.

Objective To investigate the epidemic characteristics and trends of incidence and mortality of prostate cancer in cancer registration areas in Zhejiang province from 2000 to 2009.Methods Clinical data incidence and mortality of prostate cancer were collected from 6 cancer registration areas in Zhejiang province,including Hangzhou,Jiaxing,Jiashan,Haining,Shangyu and Xianju.Crude rates,standardized rate and change trend,age-specific rates and annual percent change （APC,95% CI） of prostate cancer were checked,sorted and analyzed in Zhejiang Cancer Center.Results The prostate cancer incidence rate from 2000 to 2009 was 9.79/100 000,age-standardized incidence rates by world standard population （ASIRW） was 6.39/100 000,and the incidence cumulative risk of males aged 0-74 was 0.72% ; while the mortality rate was 2.73/100 000,age-standardized mortality rates by world standard population was 1.74/100 000,and the mortality cumulative risk of males aged 0-74 was 0.14%.Age-specific incidence of prostate cancer remained low before 50,years old and peaked at over 85-year-old group （130.30/100 000）.Age-specific mortality of prostate cancer increased after 55,and also peaked at over 85-year-old group （81.19/100 000）.The annual prostate cancer incidence rate generally grew from 1.39/100 000 （2000） to 13.89/100 000 （2009）,and the APC was 14.18% （95% CI,9.68%-18.98%）.Meanwhile,the prostate cancer mortality rate also increased from 1.52/100 000 （2000） to 3.58/100 000 （2009）,and the APC was 11.83% （95% CI,5.69%-18.33%）.Conclusion Prostate cancer incidence and mortality in Zhejiang cancer registration areas increased sharply,and the prevention and treatment of prostate cancer should be strengthened.