药源性精神异常的回顾分析

Retrospective analysis of drug-induced psychosis

目的探讨引起药源性精神异常的药品特点及一般规律。方法检索2004—2013年万方医学网与中国知网药源性精神异常的文献,对患者的性别、年龄,用药情况,精神异常的表现、发生时间及处理等进行分类统计。结果 140例患者中,60~89岁年龄段发生精神异常的比例最高;引发精神异常的药物以抗感染药居多,占62.14%;用药途径以静脉给药居多,占87.14%。结论应重视药物不良反应的监测,提高对药源性精神异常的警惕性。

Objective To discuss the characteristics and general features of drug-induced psychosis. Methods Cases involved in psychosis caused by drug repoted by Wanfang Medicine Online and China National Knowledge Infrastructure from 2004 to 2013 were indexed. The gender, age, medications, psychosis performance and time, and treatment of patients were classified statistically. Results In 140 patients, age group of 60---89 has the highest percentage of psychosis; Drugs that cause psychosis are mainly anti-infection drugs, accounting for 62.14%, and in the majority with iv drug medication route, accounting for 87.14%. Conclusion We should pay attention to the inspection of adverse drug reaction and keep a close eye on drug-induced psychosis.