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转录因子FoxM1与颅内胶质瘤治疗的研究进展

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摘要 胶质瘤是中枢神经系统最常见的原发性肿瘤,高级别胶质瘤具有高度侵袭性,术后复发快,并对放疗和化疗表现出内在抗性,患者预后不佳[1]。尽管临床医生不断探索和革新手术切除以及化学治疗和放射治疗方案,在一定程度上提高了患者术后生活质量,但一般的抗肿瘤药物,由于难以通过血脑屏障等因素的影响,治疗的效果欠佳,寻找到一个能有效治疗胶质瘤的药物就成为了研究的关键。
作者 王鑫 景治涛
出处 《中华神经外科疾病研究杂志》 CAS 2014年第5期478-480,共3页 Chinese Journal of Neurosurgical Disease Research
基金 国家自然科学基金资助项目(81101917/H1618) 辽宁省教育厅基金资助项目(L2012273) 辽宁省自然科学基金资助项目(2013021045)
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