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肿瘤细胞之间的交流 被引量：2

Cell- cell communication of cancer
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摘要 一个肿瘤细胞的产生并不意味着肿瘤发生。多个肿瘤细胞之间的对话使肿瘤成为一个异常的组织或器官。细胞接触、挤出、纠缠、迁移和变异维持着肿瘤细胞间的有序组织和肿瘤的持续生长。阻断肿瘤细胞之间的对话可能成为新的肿瘤治疗策略。 A cancer cell can not serve as cancers. Cell -cell communication is an absolute requirement for the correct functioning of cancer cells. Cell contact, cell extrusion, cell entanglement, cell migration and cell diversity contribute to development and growth of cancers as a whole. Blocking cell - cell communication may provide novel strategies in cancer treatment.
作者 张百红 岳红云
机构地区 兰州军区兰州总医院肿瘤科 兰州军区兰州总医院眼科
出处 《现代肿瘤医学》 CAS 2014年第11期2744-2746,共3页 Journal of Modern Oncology
基金 甘肃省自然科学基金项目(编号:1308RJZA181)
关键词 肿瘤 细胞接触 细胞挤出 细胞纠缠 细胞迁移 细胞变异 neoplasms cell contact cell extrusion cell entanglement cell migration cell diversity
分类号 R730.24 [医药卫生—肿瘤]
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参考文献24

  • 1Kuzdzal - Fick JJ, Fox SA, Strassmann JE, et al. High relatedness is necessary and sufficient to maintain multicellularity in Dictyosteli- um[ J]. Science,2011,334(6062) :1548 - 1551.
  • 2Navin N, Kendall J, Troge J, et al. Tumour evolution inferred by sin- gle - cell sequencing[ J]. Nature ,2011,472 (7341) :90 - 94.
  • 3Stramer BM, Dunn CA, Davis JR, et al. Rediscovering contact inhi- bition in the embryoEJJ. J Microsc,2013,251 (3) :206 -211.
  • 4Puliafito A, Hufnagel L, Neveu P, et al. Collective and single cell behavior in epithelial contact inhibition [ J ]. Proc Natl Acad Sci U S A,2012,109(3) :739 -744.
  • 5Brooke MA, Nitoiu D, Kelsell DP. Cell - cell connectivity : Desmo- somes and disease [ J ]. J Patho1,2012,226 (2) : 158 - 171.
  • 6Seeger - Nukpezah T, Golemis EA. The extracellular matrix and cil- iary signaling[ J]. Curr Opin Cell Biol,2012,24 ( 5 ) :652 - 661.
  • 7Sherer NM. Long - distance relationships : Do membrane nanotubes regulate cell - cell communication and disease progression[ J] ? Mol Biol Cell ,2013,24 ( 8 ) : 1095 - 1098.
  • 8Roberts CT Jr, Kurre P. Vesicle trafficking and RNA transfer add complexity and connectivity to cell -cell communication [ J ]. Canc- er Res, 2013,73 ( 11 ) : 3200 - 3205.
  • 9Dumortier JG, Martin S, Meyer D, et al. Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts [ J]. Proc Natl Acad Sci USA, 2012, 109 (42) : 16945 - 16950.
  • 10Ramel D, Wang X, Laflamme C, et al. Rabl 1 regulates cell - cell communication during collective cell movements [ J ]. Nat Cell Bi- ol,2013,15(3) :317 -324.

同被引文献45

  • 1樊军卫,周崇治,裘国强,唐华美,孙昱皓,彭志海.纯化结肠癌组织基因表达谱的变化[J].中华实验外科杂志,2007,24(8):905-907. 被引量：11
  • 2邢春根,杨晓东,周丽英,吴永友,蒋银芬,戴宏,吕孝东,龚巍.大肠癌细胞辐射敏感相关基因的筛选[J].辐射研究与辐射工艺学报,2007,25(4):252-256. 被引量：4
  • 3VIGNESWARAN N, WU J, SACKS P, et al. Microarray gene expression profiling of cell lines from primary and metastatic tongue squamose cell carcinoma: possible in- sights from emerging technology [ J ]. J Oral Pathol Med, 2005,34(2) :77-86.
  • 4PUTOCZKI TL, THIEM S, LOVING A, et al. Interleukin- 11 is the dominant IL-6 Family cytokine during gastroin- testinal tumorigenesis and can be targeted Therapeutially [J]. Cancer Ce11,2013,24(2) :257-271.
  • 5DU W,JIANG P, MANCUSO A, et al. TAp73 enhances the pentose phosphate pathway and supports cell prolifera- tion [ J ]. Nat Cell Biol, 2013,15 ( 8 ) :991-1000.
  • 6NAGARAJANA R, UPRETI M. Qualitative assessment of gene expression in affymetrix gene chip arrays [ J ]. Physi- ca A ,2007,373 ( 3 ) :486-496.
  • 7CHEN M H,LBRAHIM J G,, CH! Y Y. A new class of mixture models for differential gene expression in DNA miemarray data[ J ]. J Stat Plan Inference ,2008,138 (2) : 387-404.
  • 8RAMACHANDRAN N, RAPHAEL J V, HAINSWORTH E, et al. Next-generation high-density self-assembling function protein arrays [ J ]. Nat Methods, 2008,5 ( 6 ) : 535 -538.
  • 9WANG K, GAN L, JEFFERY E, et al. Monitoring gene ex- pression profile changes in ovarian carcinomas using cD- NA microarray [ J ]. Gene, 1999,229 (12) : 101-108.
  • 10KATO T,SATOH S,OKABE H,et al. Isolation of a novel human gene, MARKLI, homologous to MARK3 and its in- vovenmemt in hepatocellular carcinogenesis [ J ]. Neopla- sia,2001,3 ( 1 ) :49.

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现代肿瘤医学
2014年 第11期

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