胆囊结石患者围术期血栓弹力图与常规凝血试验相关性分析

Analysis of Correlation between TEG and Conventional Coagulation in Perioperative Period in Gallstone Patients

目的探讨胆囊结石患者围术期血栓弹力图(TEG)各参数与常规凝血试验各指标的相关性,评价两种方法在围术期检测凝血状况的价值。方法选择100例需手术治疗的胆囊结石患者和80例正常对照组,所有受试者均同步进行血栓弹力图(TEG)检测与常规凝血试验。结果胆囊结石组R值和K值明显缩短,α角、MA值和CL值明显增大,表明患者存在血液高凝状态。R值与凝血酶原时间(PT)、凝血酶原时间国际标准化比值(PT-INR)、活化部分凝血酶时间(APTT)呈正相关,与纤维蛋白原(FIB)呈负相关。α角与PT、PT-INR、APTT呈负相关。MA值与FIB呈正相关,与PT、PT-INR、APTT呈负相关。结论胆囊结石患者围术期血栓弹力图指标与常规凝血试验指标存在明显相关性,两者可起到互补作用。血栓弹力图检测对于评估凝血全貌,判断出血风险、指导输血有重要的意义。

Objective To investigate the relationship between TEG and conventional coagulation in the patients with gallstone and evaluate the similarities and differences of these two Methods.Methods TEG and conventional coagulation were detected in perioperative period in 100 gallstone patients and 80 cases of normal control group.Results In the patients,the value of R and K were obviously shorter,and the value of α,MA and CL were enlarged.R had the positive correlation with PT,INR and APTT,and had negative correlation with FIB.The value of αnegatively correlated with PT,INR and APTT.The value of MA positively correlated with FIB,and negatively correlated with PT,INR and APTT.Conclusion There is significant correlation between TEG and conventional coagulation in perioperative period in gallstone patients.Detection of TEG has an important significance to assess the coagulation picture,judge the risk of bleeding and guide blood transfusion.