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银屑病基因-环境、基因-基因交互作用研究进展 被引量：3

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摘要 目前认为银屑病主要由环境因素和遗传因素等共同作用所致.环境因素如吸烟、饮酒、外伤等可诱发或加重银屑病病情.遗传学研究发现,PSORS 1-9、HLA-Cw＊0602、IL12B、IL23R、ERAP1等位点或基因与银屑病的易感性相关联.近年来,研究者利用多种方法开展银屑病基因-环境、基因-基因交互作用方面的研究,阐明其在银屑病发病机制中的作用,取得了进展.
作者 沈长兵 尹先勇 杨森 张学军
机构地区 安徽医科大学第一附属医院皮肤性病科/皮肤病研究所
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2014年第11期835-838,共4页 Chinese Journal of Dermatology
基金 国家自然科学基金青年基金（81000692）、国家自然科学基金青年一面上连续资助项目（81370044）
关键词 基因-基因交互作用 基因-环境 银屑病 HLA-Cw＊0602 环境因素 遗传因素 发病机制 遗传学
分类号 R758.63 [医药卫生—皮肤病学与性病学]
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共引文献19

同被引文献25

  • 1徐逸萍,李建华.窄波UVB联合郁金银屑片治疗寻常型银屑病的体会[J].现代养生,2014,0(20):119-119. 被引量：1
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中华皮肤科杂志
2014年 第11期

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