期刊文献+

结直肠癌肝转移的外科治疗策略 被引量:4

原文传递
导出
摘要 结直肠癌是人类常见的消化系统恶性肿瘤,发病率逐年增高,居男性恶性肿瘤发病率第3位,女性发病率第2位[1].我国结直肠癌发病率在所有恶性肿瘤中位居第3位,仅次于肺癌及胃癌[2].肝脏是结直肠癌转移最主要的靶器官,按照国际通用分类方法,结直肠癌肝转移(colorectal liver metastasis,CRLM)可分为同时性肝转移和异时性肝转移.同时性肝转移是指结直肠癌确诊时发现的或结直肠癌原发灶根治性切除术后6个月内发生的肝转移,发生率为15% ~25%;而另外15% ~25%的患者在结直肠癌根治术6个月后发现肝转移,称为异时性肝转移[3-6].无肝转移的结直肠癌患者5年生存率为70%~96%,而发生CRLM的患者5年生存率仅为25%~45%[7].CRLM是大多数结直肠癌患者死亡的主要原因[8].
出处 《中华外科杂志》 CAS CSCD 北大核心 2014年第11期866-868,共3页 Chinese Journal of Surgery
  • 相关文献

参考文献33

  • 1Jemal A, Bray F, Center MM, et al. Globat cancer statistics [ J ]. CA Cancer J Clin,2011,61 (2) :69-90.
  • 2郝捷.2012中国肿瘤登记年报[M].北京:军事医学科学出版社.2012.
  • 3Alberts SR, Horvath WL, Sternfeld WC, et al. Oxaliplatin, fluorouracil, and leucovorin for patients with unresectable liver- only metastases from colorectal cancer: a North Central Cancer Treatment Group phase Ⅱ study [ J ]. J Clin Onco1,2005,23 (36) : 9243-9249.
  • 4Kemeny N. Management of liver metastases from colorectal cancer [Jl. Oncology (Williston Park) ,2006,20(10) :1161-1176.
  • 5Muratore A, Zorzi D, Bouzari H, et al. Asymptomatic colorectal cancer with un-resectahle liver metastases: immediate colorectal resection or up-front systemic chemotherapy? [ J ]. Ann Surg Oncol,2007,14 ( 2 ) : 766 -770.
  • 6Van Cutsem E, Nordlinger B, Adam R, et al. Towards a pan- European consensus on the treatment of patients with colorectal liver metastases [ J ]. Eur J Cancer,2006,42 (14) : 2212-2221.
  • 7Yoo PS, Lopez-Soler RI, Longo WE, et al. Liver resection for metastatic colorectal cancer in the age of neoadjuvant chemotherapy and bevacizumab [ J ]. Clin Colorectal Cancer,2006, 6(3 ) :202-207.
  • 8Helling TS, Martin M. Cause of death from liver metastases in colorectal cancer[ J]. Ann Surg Oncol,2014,21 (2) :501-506.
  • 9Sharma S, Camci C, Jabbour N. Management of hepatic metastasis from colorectal cancers:an update [ J ]. J Hepatobiliary Pancreat Surg,2008,15 (6) :570-580.
  • 10Yang AD, Brouquet A, Vauthey JN. Extending limits of resection for metastatic colorectal cancer : risk benefit ratio [ J ]. J Surg Oncol,2010,102 (8) :996-1001.

二级参考文献24

  • 1秦新裕,许剑民,刘凤林,钟芸诗.进展期消化道肿瘤术前介入治疗的评价[J].中国实用外科杂志,2005,25(5):307-309. 被引量:13
  • 2Sadahiro S, Suzuki T, Ishikawa K, et al. Recun'ence patterns after curative resection of colorectal cancer in patients followed for a minimum often years. Hepatogastroenterology,2003, 50:1362- 1366.
  • 3Bentrem DJ, DeMatteo RP, Blumgart LH. Surgical therapy for metastatic disease to the liver. Ann Rev Med,2005 ,56 :139-156.
  • 4Adam R. Current surgical strategies for the treatment of colorectal cancer liver metastases. Eur J Cancer, 2004, 2:21-26.
  • 5Scheele J, Stang R, Altendorf-Hofmann A, et al. Resection of colorectal liver metastases. World J Surg, 1995, 19: 59-71.
  • 6Garden O J, Rees M, Poston G J, et al. Guidelines for resection of colorectal cancer liver metastases. Gut,2006,55 Suppl 3:1-8.
  • 7Otchy D, Hyman NH, Simmang C, et al. Practice parameters for colon cancer. Dis Colon Rectum,2004,47:1269-1284.
  • 8Pawlik TM, Scoggins CR, Zorzi D, et al. Effect of surgical margin status on survival and site of recurrence after hepatic resection for colorectal metastases. Ann Snrg, 2005,241 : 715- 722.
  • 9Adam R. Treatment of liver metastasis of colorectal cancer. Eur J Cancer,2009,7 ( s2 ) :60-68.
  • 10Imamura H, Seyama Y, Kokudo N, et al. Single and multiple resections of multiple hepatic metastases of colorectal origin. Surgery ,2004,135:508-517.

共引文献107

同被引文献22

引证文献4

二级引证文献5

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部