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血清降钙素原定量在细菌血流感染诊断中的临床价值 被引量:19

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摘要 目的:探讨血清降钙素原(PCT)定量在细菌血流感染诊断中的临床价值。方法:收集符合实验要求的细菌血流感染及非细菌血流感染患者各100例,以C反应蛋白(CRP)、中性粒细胞绝对值(ANC)为对比指标,采用ROC曲线评估PCT诊断细菌血流感染及区分革兰阴性杆菌和革兰阳性球菌血流感染的临床价值。结果:PCT、CRP、ANC诊断细菌血流感染AUROCC分别为0.951、0.747、0.688,PCT诊断细菌血流感染OOP为1.83 ng/m L,灵敏度、特异性、PPV、NPV分别为83%、93%、92%、85%。PCT、CRP、ANC区分革兰阴性杆菌和革兰阳性球菌血流感染AUROCC分别为0.946、0.663、0.581,PCT区分革兰阴性杆菌和革兰阳性球菌血流感染OOP为2.96 ng/m L,灵敏度、特异性、PPV、NPV分别为97%、78%、92%、74%。结论:血清PCT定量可作为诊断细菌血流感染及区分革兰阴性杆菌和革兰阳性球菌血流感染实验室指标。
出处 《实用医学杂志》 CAS 北大核心 2014年第21期3512-3514,共3页 The Journal of Practical Medicine
基金 清远市科技计划项目(编号:2012B011204124)
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