白癜风患者血清IL-22、IL-6和TNF-α水平的检测

Detection of serum IL-22,IL-6 and TNF-α in patients with vitiligo

目的:检测白癜风患者血清IL-22、IL-6和TNF-α水平,探讨上述因子在白癜风发病中的可能作用。方法:采用酶联免疫吸附法检测30例白癜风患者和30例正常对照者血清IL-22、IL-6和TNF-α的水平。结果:白癜风患者血清IL-22、IL-6和TNF-α的水平显著高于正常对照组(P<0.05)。结论:IL-22、IL-6和TNF-α可能参与了白癜风的发病过程。

Objective：To detect the levels of IL-22, IL-6 and TNF-α in serum of patients with vitiligo and investigate the role of them in the onset of vitiligo. Methods：The levels of IL-22, IL-6 and TNF-αwere detected by ELISA in 30 patients with vitiligo and 30 healthy controls. Results： The levels of IL-22, IL-6 and TNF-α in the patients with vitiligo were significantly higher than those in healthy controls （P〈0.05）. Conclusion：IL-22, IL-6 and TNF-α may be involved in the pathogenesis of vitiligo.