成人急性淋巴细胞白血病的诊疗进展

Advances in the diagnosis and treatment of adult acute lymphoblastic leukemia

急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)是一种常见的恶性血液疾病。虽然成人ALL患者在诱导缓解治疗后完全缓解率可达80%以上,但大多数患者最终出现复发,长期生存率低。本研究对近年来成人ALL诊疗的进展进行综述,为成人ALL患者的诊疗提供参考和依据,以进一步改善该类患者的生存质量。

Acute lymphoblastic leukemia （ALL） is a common hematopoietic malignancy. The initial complete remission rates of adult ALL reach over 80%, but most of the patients eventually relapse and the long-term survival re-mains poor. This article reviewed advances in the biological features and treatment of adult ALL during the past decade with a view to further improving the survival quality rate of the patients.