儿童尖锐湿疣的流行病学及治疗的研究进展

Epidemiology and treatment of childhood condyloma acuminatum： an update

尖锐湿疣是人乳头瘤病毒所引起的性传播疾病.近年来,儿童患病的报道有所增加,其传播途径多样,不能忽略性虐待的可能,儿童感染人乳头瘤病毒类型及临床表现有别于成年人.儿童尖锐湿疣的治疗主要包括物理治疗、手术治疗、局部药物治疗等.选择治疗方案需要充分考虑安全性、有效性及耐受性,目前尚无美国食品药品监督管理局批准的可用于治疗＜ 12岁儿童尖锐湿疣的药物.

Condyloma acuminatum （CA） is a sexually transmitted disease caused by human papillomavirus （HPV）.In recent years,reports on childhood CA have increased.Childhood CA is transmitted via various routes and the possibility of sexual abuse cannot be ignored.Meanwhile,HPV type and clinical manifestations are different between childhood and adult CA.The treatment of childhood CA includes physical therapy,surgery,topical medications,and so on.Safety,efficacy and tolerability should be fully considered in selection of treatment protocols.For CA in children under 12 years of age,there are no treatments approved by the United States Food and Drug Administration.