男性包皮环切对降低生殖道感染和预防生殖道肿瘤的意义

Long-term benefit of male circumcision to the reduction of urinary tract infections and genitourinary cancers in China

越来越多的的研究结果证明,男性包皮环切显著降低包皮龟头炎和尿路感染及其他生殖道感染、降低HIV和HPV以及HSV-2与其他性传播疾病感染风险,对生殖道肿瘤,如子宫颈癌、阴茎癌和前列腺癌具有预防作用。目前在中国包皮环切率低于5%。商环包皮环切术在非洲的临床评估试验和大样本随机对照试验结果证实,商环具有安全性好、可接受性和满意度高。世界卫生组织(WHO)和联合国艾滋病规划署(UNAIDS)已将男性包皮环切推荐为艾滋病预防策略的重要干预措施之一,中国应该大力提倡安全的包皮环切术,从而降低男性及其女性伴侣生殖道感染、预防生殖道肿瘤,对改善全民生殖健康具有长期影响和深远意义。研究男性包皮环切对公共卫生的深远影响将成为今后泌尿男科工作的重点之一。

Increasingly accumulated results from randomized controlled trials and other clinical studies have demonstrated that male circumcision reduces the risks of acquisition and transmission of HIV,HPV,HSV-2,and other sexually transmitted infections,and thus has a potential role in preventing cervical cancer,penile cancer and prostate cancer. The prevalence of male circumcision in China is currently less than 5%. The clinical evaluation studies and randomized controlled trials of the Shang Ring device showed excellent safety profiles,extremely high acceptability,and satisfaction among the participants and service providers in Africa and China.Given the recent recommendations by the World Health Organization and the Joint United Nations Program on HIV / AIDS（ UNAIDS）,voluntary medical male circumcision should be promoted in China at the national level as an important alternative intervention to reduce reproductive tract infections and prevent both males and females from reproductive tract cancers. More emphasis is required on the studies of the long-term health benefits of male circumcision in uro-andrology.