均匀设计法优选连翘半仿生提取工艺

Optimization of Semi-bionic Extraction Technology of Forsythia Suspensa by Uniform Design

目的:优选连翘的半仿生提取工艺条件。方法:以连翘酯苷A、连翘苷的含量和干浸膏得率为综合评价指标,采用均匀设计法优选连翘半仿生提取工艺。结果:通过优化试验并将试验结果经过DPS数据处理,确定最优条件并结合生产实际,确定三煎用水的pH依次为2.0,7.0,10.0;煎煮时间依次为:1,0.5,0.5 h。结论:本法为连翘的优化提取提供了理论依据。

Objective：To optimize semi-bionic extraction（SBE）of Forsythia suspensa. Methods： The best conditions of semi-bionic extraction of Forsythia suspense were screened by uniform design with the total content of forsythoside A,and forsythin and dried extract weight as the indices. Results：The results of the uniform design were analyzed by DPS data, and combined with the industrial production conditions, the optimal extraction technology was as follows：the pH value of water in the three-time extraction was 2. 0,7. 0 and 10. 0 with the extraction time of 1. 0h,0. 5h and 0. 5h, respectively. Conclusion： The technology provides a theoretical basis for the extraction optimization of Forsythia suspensa.