糖尿病性黄斑水肿光学相干断层扫描形态学分类的临床分析

Clinical analysis of optical coherence tomographic features in clinically significant diabetic macular edema

目的 探讨糖尿病性黄斑水肿光学相干断层扫描的形态学分类各型间的对比分析.研究对象临床有意义糖尿病性黄斑水肿（CSME）患者55例102眼.方法 对CSME组患者进行OCT检查,观察OCT检查的图像特征、分类,并将各种类型的黄斑中心凹中心厚度、最佳矫正视力、糖尿病病程、空腹血糖等临床资料进行对比分析.结果 在OCT分类中,中心凹中心厚度值及最佳矫正logMAR视力在各组间均有显著性差异（P值=0.000,P＜0.05）,糖尿病病程及空腹血糖在各组间无显著性意义（P值分别为0.306和0.752,P＞0.05）.结论 糖尿病性黄斑水肿患者的视力预后与黄斑中心凹中心厚度以及黄斑水肿的类型有关;黄斑中心凹中心厚度可作为诊断黄斑水肿的客观定量的重要指标.

Objective To discuss the contrast analysis between types of diabetic macular edema classified by optical coherence tomographic features. 55 cases （102 eyes） with clinical significant diabetic macular edema（CSME） were involved. Methods All cases were taken OCT inspection and classified to different types by image characteristics. The central thickness of macular fovea, best corrected visual acuity （BCVA）, course of disease, fasting plasma glucose （FPG） were analyzed. Results The central thickness of macular fovea and BCVA were different between each types （P〈0.05）. Conclusion Vision prognosis is related with central thickness of macular fovea and characteristics of CSME. The central thickness of macular fovea can be selected as an objective index for diagnosis of CSME.