传统综合训练与智能化多维视觉训练对屈光不正性弱视的疗效对比及其影响因素研究

Efficacy of traditional combination therapy and intelligent multi-dimensional training for ametropic amblyopia and its influencing factors

目的研究传统综合训练与智能化多维视觉训练治疗屈光不正性儿童弱视的疗效差异以及相关影响因素。方法选取2010年7月至2012年9月在我院眼科治疗的弱视儿童患者200例,根据治疗方法的不同分为观察组(智能化多维视觉训练组,100例)和对照组(传统综合训练治疗组,100例),分别给予智能化多维视觉训练和传统综合训练治疗,比较两组患儿的疗效及相关影响因素。结果观察组治愈70例,进步27例,无效3例;对照组治愈35例,进步45例,无效20例;观察组患儿的疗效显著优于对照组,差异有显著统计学意义(χ2=28.73,P<0.01)。在远视患儿中,观察组的疗效显著优于对照组,差异有显著统计学意义(χ2=11.43,P<0.01),而2组近视和散光患儿疗效差异均无统计学意义(χ2=0.159、0.583,均为P>0.05)。在3-6岁(χ2=10.30,P<0.01)、>6-9岁(χ2=6.665,P=0.036)两个年龄段,观察组患儿的疗效优于对照组,而2组>9-15岁患儿疗效差异并无统计学意义(χ2=1.895,P>0.05)。在不同治疗时间内,观察组患儿治愈率显著高于对照组,差异有显著统计学意义(χ2=20.14,P<0.01)。结论智能化多维训练相对于传统综合疗法,治疗屈光不正性弱视患儿疗效更佳,且患儿屈光不正类型、发病年龄及治疗时间明显影响疗效。

Objective To analyze the efficacy of traditional combination therapy and intelligent multi-dimensional training for ametropic amblyopia and its influencing factors. Methods Clinical data of 200 children with ametropic amblyopia received treatment at our hospital from July 2010 to September 2012 was retrospectively analyzed. Patients were divided into two groups according to the treatment： Observation group（ intelligent multi-dimensional training） and control group（ traditional combination therapy）,100 cases in each group. The efficacy of different treatments and influencing factors of therapeutic effect between two groups was analyzed. Results The efficacy of children in observation group were cured in 70 cases,improved in 27 cases,unef-fective in 3 cases,which in control group were 35 cases,45 cases and 20 cases,respectively,there was significant difference（ χ^2= 28. 73,P〈0. 01）. For the children with hyperopia,the therapeutic effect of the observation group was significantly better than the control group（ χ^2= 11. 43,P〈0. 01）,but no difference was found in children with myopia and astigmatism between two groups（ χ^2= 0. 159,0. 583,all P〉0. 05）. For the children aged from 3 years to 6 years（ χ^2= 10. 30,P〈0. 01）,6 years to 9 years（ χ^2= 6. 665,P = 0. 036）,the efficacy in observed therapy group was significantly better than the control group,but no difference was found in children aged from 9 years to 15 years between two groups（ χ^2= 1. 895,P〉0. 05）. The efficacy in observed therapy group was significantly better than the control group with the same time of treatment（ χ^2= 20. 14,P〈0. 01）. Conclusion Intelligent multi-dimensional training is significantly better than traditional combination therapy for children with ametropic amblyopia,and the efficacy are influenced by the factors such as the type of ametropia,age of onset and duration of treatment.