针刺治疗室上性心动过速有效性与安全性系统评价与Meta分析

Effectiveness and safety of acupuncture for supraventricular tachycardia:a systematic review and Meta-analysis

系统评价针刺治疗室上性心动过速(室上速)的有效性和安全性。检索国内外各数据库中针刺治疗室上速的随机对照试验,用Cochrane Handbook 5.1.0中的偏倚风险评估工具对文献进行偏倚风险评估,用RevMan 5.2软件进行统计和Meta分析。5个研究包括323例病例被纳入,结果表明针刺治疗较空白对照多降低心率18.8次/min[95%CI(12.68,24.92)];临床有效率优于地尔硫卓组,[OR=3.11,95%CI(1.50,6.46)];与心律平的即时效应无显著差异。5项研究皆未提及不良反应。目前证据提示针刺治疗室上速安全有效,但证据等级较低,结论论证强度有待提高。

The effectiveness and safety of acupuncture for the treatment of supraventricular tachycardia were systematically reviewed.The randomized controlled trials（RCTs）regarding acupuncture for supraventricular tachycardia were searched in domestic and overseas databases,and the evaluation tool of bias risk in Cochrane Handbook 5.1.0software was used to perform the evaluation of bias risk in literature,and RevMan 5.2software was applied for statistics and Meta-analysis.Five RCTs involving 323 patients were included.The results showed that compared with the blank control group,the acupuncture reduced the heart rate by 18.8times/min [95% CI（12.68,24.92）];the clinical effective rate in the acupuncture group was superior to that in the diltiazem group[OR=3.11,95%CI（1.50,6.46）];the difference of immediate effect between propafenone and acupuncture was not significant.No reports regarding adverse events was described in 5RCTs.As was shown in the present evidence,acupuncture is safe and effective for the treatment of supraventricular tachycardia,but the level of evidence was low and the intensity of conclusion needed to be improved.