摘要
Tregs细胞的免疫调控作用在维持机体稳态上发挥重要作用。miRNA是一种重要的调节因子,在器官的发育,细胞分化、平衡和功能上起重要作用。Tregs细胞表达特异性miRNA,miRNA亦参与Tregs细胞分化、发育及功能。为此,本文对miRNA在Tregs细胞发育、功能等方面发挥的作用作一综述。
The regulatory T cells(Tregs) play a critical role in maintaining immune homeostasis. MicroRNA(miRNA), a very important transcription factor, is significant for the organ development, cell differentiation, balance and function. Tregs may express specific miRNA, as well as miRNA also involves in Tregs differentiation,development and function. In this review, we try to give a brief introduction on the regulatory role of miRNA on the Tregs differentiation and function.
出处
《免疫学杂志》
CAS
CSCD
北大核心
2014年第11期1021-1024,共4页
Immunological Journal
基金
国家自然科学基金(81373154)
辽宁省博士科研启动基金(20121121)