摘要
免疫异常是肾小球疾病发病的重要机制之一,免疫抑制剂在肾小球疾病的治疗中占有举足轻重的地位。免疫抑制剂的种类繁多,肾小球疾病根据临床病理表现不同,对免疫抑制剂存在不同的反应性。2012年改善全球肾脏病预后组织(KDIGO)制订的临床实践指南规范了常见免疫抑制剂的适应证、剂量和疗程。本文对2012年KDIGO指南中肾小球肾炎的免疫抑制剂使用进行了大致总结和评论。
Immune disturbance is one of the most important mechanisms of glomerulonephropathy. lmmunosuppressants play a critical role in the treatment of glomerulonephropathy. There are a variety of immunosuppressants. Different clinical and pathological manifestations in patients with glomerulonephropathy can reveal different responses to immunosuppressants. In 2012, the Kidney Disease： Improving Global Outcomes （KDIGO） clinical practice guidelines standardized the indications, dosages, and courses of treatment with the immunosuppressants. In this paper, we summarized and discussed the applications of immunosuppressants in treatment of glomerulonephritis according to the KDIGO guidelines.
出处
《中华肾病研究电子杂志》
2014年第4期1-4,共4页
Chinese Journal of Kidney Disease Investigation（Electronic Edition）
关键词
免疫抑制剂
肾小球疾病
指南
Immunosuppressant
Glomerulonephropathy
Guidelines
