氦氖激光联合更昔洛韦治疗带状疱疹的疗效观察

Observation on the curative effect of He-ne laser combined with ganciclovir on shingles

目的:探讨氦氖激光联合更昔洛韦治疗带状疱疹的临床疗效。方法:选择86例带状疱疹患者随机分为对照组和观察组两组,分别43例,对照组患者使用更昔洛韦0.25 g,1次/d静脉注射治疗;观察组患者在对照组治疗的基础上联合使用氦氖激光于疼痛部位及皮损处直接照射10 min,1次/d,两组均连续治疗7 d,对两组治疗的效果进行比较。结果:观察组治疗的总有效率为95.3%,明显高于对照组的60.5%,差异有统计学意义(P<0.05),观察组患者的水泡结痂时间、疼痛缓解时间和皮损愈合时间明显短于对照组,差异有统计学意义(P<0.05)。结论:氦氖激光联合更昔洛韦治疗带状疱疹可明显缩短患者的炎性反应和渗出时间,加快组织愈合,临床效果显著。

Objective To observe the curative effect of He - ne laser combined with ganciclovir on shingles. Method 86 shingles pa-tients were selected and divided into two groups. In control group,43 patients were treated by ganciclovir 0. 25 g. In observation group,43 patients were treated by ganciclovir 0. 25 g combined with he - ne laser. Both groups of patients were treated for 7 days. The effects of two groups were compared. Results The total effective rate of observation group was 95. 3% and the total effective rate of control group was 60. 5%. The differences were statistically significant（P 〈 0. 05）. The vesicular scab time,pain relief time,skin lesion healing time of ob-servation group were all less than control group,the differences were statistically significant（P 〈 0. 05）. Conclusion He - ne laser com-bined with ganciclovir on shingles can significantly reduce vesicular scab time and skin lesion healing time and promote tissue healing. The clinical effect is remarkable.