脓毒血症病例总结并文献复习

Literature review of sepsis cases

目的通过报告脓毒血症的诱因、临床表现、治疗和预后,加深认识,掌握该病预防、诊断、治疗。方法回顾性分析医院确诊的1例脓毒血症患者临床资料,报道患者由单一疾病恶化为脓毒血症多器官、多系统的典型动态病变过程,展示主要检验指标及影像学资料;通过分析病因、诊断及治疗过程,结合文献资料复习,将所涉及各个专科知识点汇总,将治疗重症感染的抗菌药物的抗菌谱、适应证及禁忌证等进行系统学习,同时介绍数种目前最新上市的抗菌药物,开阔视野。结果该患者经选用敏感及强效抗菌药物,康复出院,各器官功能逐渐恢复,无后遗症。结论脓毒血症是重症感染,重视源头选择适当的抗菌药物,对于合并多器官功能衰竭者,需联合各专科的力量,选用最佳治疗方案。

OBJECTIVE To deepen the understanding of the sepsis through exploration of the predisposing factors , clinical manifestations ,treatment ,and outcomes so as to provide guidance for the prevention ,diagnosis ,and treatment .METHODS The clinical data of 1 patient with confirmed sepsis were retrospectively analyzed ,the single sepsis in the reported case deteriorated into the multi‐organ ,multi‐system typical dynamic lesions ,the major labo‐ratory indicators and the imaging data were defined ;the special knowledge involving different clinical departments was summarized through the analysis of etiology ,diagnosis and treatment in combination with the literature re‐view .The antibacterial spectrum of antibiotics used for severe infections ,indications ,and contraindications were systematically studied ,and dozens of novel antibiotics were introduced in order to broaden the horizons .RESULTS The patients who were treated with sensitive and powerful antibiotics were recovered and discharged ,the functions of various organs gradually recovered without sequelae .CONCLUSION Sepsis is a severe infection .It is necessary to pay great attention to the sources and choose appropriate antibiotics ;for the patients complicated with multiple or‐gan failure ,the various departments should join their efforts to choose the optimal program .