重庆某城区儿童青少年男性青春期性征发育流行病学研究

Epidemiological investigation of puberty development among school-aged boys in Chongqing urban

目的了解重庆某城区6-20岁男性儿童青少年青春期性征发育现状,以及该群体性早熟发生率。方法采用分层随机整群抽样方法,共抽取6-20岁男性儿童青少年2 189名,检测青春期第二性征发育数据：首次遗精年龄、睾丸体积、外生殖器、阴毛。9岁前阴毛、外生殖器达TannerⅡ期（P2、G2）,或睾丸体积达4mL者被定义为性早熟。结果城镇男性儿童青少年首次遗精年龄、阴毛、外生殖器开始发育的年龄均早于农村男性儿童青少年,其中外生殖器开始发育年龄两者差异有统计学意义（P〈0.05）。9岁以下男性儿童青少年545名,依据睾丸体积≥4mL、外生殖器发育达到G2、阴毛发育达到P2诊断的性早熟率分别为2.8%、0.6%、0.0%。结论重庆某城区男性儿童青少年首次遗精、睾丸、外生殖器及阴毛开始发育的年龄存在城、乡差别,且有性早熟情况发生,应广泛开展男性青春期发育的相关研究,为建立适用于我国儿童青少年青春期发育评定标准提供依据。

Objective To determine the current status of pubertal development and prevalence of sexual precocity a- mong Chongqing urban school-aged boys. Methods A total of 2 189 boys aged 6-20 years old were recruited by using multiple-stage stratified cluster sampling method. The sexual characteristics development was inspected, including the first spermatorrhea age, testicular volume,genitalia and pubes. Sexual precocity was defined as onset of P2, G2 or one-sided testicular volume 4 mL before 9 years old. Results The sexual characteristics development age of urban boys was younger than rural boys,and the first development age of external organs of generation had difference （P〈0. 05）. A total of 545 boys were younger than 9 and the prevalence rates of sexual precocity according to testicular size,G2 and P2 were 2.8% ,0.6%, and 0.0% respectively. Conclusions Difference of pubertat development staging between urban boys and rural boys is observed in this study. More studies on pubertal development in boys are necessary.