冠脉临界病变的中医证候文献回顾与分析

Literature reviewing and analyzing the patterns of traditional chinese medicine for borderline coronary lesions

目的冠脉临界病变为冠心病的一个特定阶段,其中医证候的研究将对其临床治疗方案有重要的意义。方法本文利用文献检索的方法,检索国内从1979年1月截止到2013年12月的冠心病研究论文和学位论文,筛选了利用冠脉造影检查分类血管狭窄程度并进行中医辨证的研究,归纳总结出冠脉临界病变的中医辨证分型。结果有17篇论文入选,共682例冠脉临界病变病例,其中心血瘀阻证和痰阻心脉证为冠脉临界病变的主要证型,分别占29.33%和15.4%,心肾阴虚、心阳亏虚、气阴两虚和痰瘀互结也占有一定的比例。结论冠脉临界病变的主要中医证型是心血瘀阻证和痰阻心脉证。

Objective Borderline coronary lesions is a special stage for the coronary heart dis-ease. It is important to study the patterns of traditional Chinese medicine and make a strategy for treatment in clinic. Methods The literature retrieval method is used in this study. We retrieved all Chinese pub-lished research papers, and academic dissertations from January 1979 to December 2013. In these articles, coronary angiogram examination was used to distinguish the degree of coronary artery stenosis and traditional Chinese medicine syndrome differentiation was applied to study the disease. Then we summarized the pat-terns of borderline coronary lesions. Results 17 articles and 682 cases of borderline coronary lesions in total were included in the study. We found that blood stasis pattern and phlegm blocking patteren were the main patterens for borderline coronary lesions, which were 29. 33% and 15. 4% respectively. Pattern of heart-kidney yin deficiency, pattern of heart yang deficiency, dual deficiency of qi and yin, pattern of phlegm and blood stasis binding together also possessed certain proportions. Conclusion The blood stasis pattern and phlegm blocking patteren were the two main patterns for borderline coronary lesions.