基于医院信息系统的帕金森病患者临床特征分析

Analysis on Clinical Characteristics of Parkinsonism Inpatients Based on Hospital Information System

目的基于医院信息系统（HIS）分析帕金森病患者的临床特征。方法采集2008年1月至2010年12月全国17家三级甲等医院4497例帕金森病住院患者信息,对患者西医诊断、中医证候信息进行规范化后,提取患者一般资料及中医证候信息进行频次统计。结果 4497例患者中男性2582例,女性1658例,性别记录缺失者257例。年龄中位数为69岁,年龄分布以46~65岁多见,共962例（36.10%）。住院天数中位数为12天,以8~14天多见,共1920例（42.70%）。住院总费用中位数为10665.4元,以5001~10 000元多见,共1 235例（29.29%）。有入院主证记录的43例患者中,肝风内动证21例（48.84%）、痰瘀阻络证10例（23.26%）、其他证共计12例（27.91%）;有出院主证记录的146例患者中,肝风内动证29例（19.86%）、肝肾阴虚证61例（41.78%）、气血亏虚证14例（9.59%）、痰瘀阻络证13例（8.90%）、其他证共计29例（19.86%）。结论帕金森病多发于中老年人群,男性相对多见,其中医证候以肝肾阴虚及肝风内动为主。

Objective To analyze the clinical characteristics of Parkinsonism patients based on hospital informa- tion system （HIS）. Methods Information of 4, 497 Parkinsonism inpatients was collected in 17 tertiary A hospi- tals nationwide from January 2008 to December 2010. The information on western medicine diagnosis and traditional Chinese medicine （TCM） syndrome was normalized. The general data and TCM syndrome information was extracted for frequency statistics. Results Among 4497 patients, 2 582 were male （60. 90% ） and 1 658 （39. 10% ） were female. The median age was 69 years old. Most patients （962 cases, 36. 10% ） aged from 46 years old to 65 years old. The median length of hospital stay was 12 days. The hospital stay of most patients （ 1 920 cases, 42.70% ） was 8 to 14 days. The median hospitalization expense was 10665.4 yuan. Most patients （1235 cases, 29.29% ） spent 5001 to 10000 yuan. In 43 patients with admission syndrome record, 21 patients were with syndrome of up-stirring of the liver （48.84%）, 10 patients with syndrome of phlegm and stasis obstructing the collateral （23.26%）, and the rest 12 patients with other syndromes （27.91%）. In 146 patients with discharge syndrome record, 29 patients were with syndrome of up-stirring of the liver （ 19. 86% ）, 61 patients with syndrome of yin-deficieney of liver and kidney （41.78%）, 14 patients with syndrome of deficiency of qi and blood （9.59%） , 13 patients with syndrome of phlegm and stasis obstructing the collateral （8.90%）, and the rest patients were with other syndromes （ 19. 86% ）. Con- clusion Parkinsonism mostly strikes middle-aged and old people, and it is relatively common in male. The main TCM syndromes in Parkinsonism patients are yin-defieiency of liver and kidney and up-stirring of the liver.