我院256例药品不良反应报告分析

Analysis of 256 Adverse Drug Reaction Reports in Our Hospital

目的了解我院药品不良反应的发生情况。方法对我院2013年1月―2014年9月上报至国家药品不良反应监测系统的256例ADR报告进行统计、分析。结果 256例ADR报告中男性ADR发生率(44.9%)低于女性(55.1%),≤18岁和≥60岁的有120例(46.88%);静脉滴注引起的ADR211例(82.42%);其中抗感染药物引起的ADR最多,有106例(41.41%),中药注射剂36例(14.06%);严重及新的ADR有16例,占6.25%;ADR累及系统以皮肤及附件损害最常见,有104例,占37.01%。结论应继续加强ADR监测工作,尤其是合理使用抗感染药物和中药注射剂,减少ADR的发生。

Objective To investigate the general status of ADR in our hospital. Methods By a retrospective study, a total of 256 ADR cases reported to ＂Nationwide Adverse Drug Reaction Monitoring Network＂ were collected From Jan. 2013 to Sep. 2014 in our hospital for statistical analysis. Results Of the 256 cases, males（44.9%）showed lower proportion than females（55, l%）;120cases（46.88%）were received in patients aged 〈18 and 〉60;211 cases （82.42%） were caused by intravenous administration; 106 cases （41.41%） were induced by antiinfectives, and 36 cases （14.06%） by TCM injections.There were 16 cases severe and new cases （6.25%） ;104 cases（37.01%）were reported on the Lesions of skin and its appendants. Conclusion Clinical staff should strengthen ADR monitoring especially on use antiinfectives and TCM injections rationally in order to decrease the occurrenceofADR.