纳洛酮和单唾液酸四己糖神经节苷脂治疗颅脑损伤的间接Meta分析

Comparison Between Naloxone and Monosialoteterahexosyl Ganglioside in Treating Head Injury:An Indirect Meta-analysis

目的:系统评价纳洛酮和单唾液酸四己糖神经节苷脂(GM1)治疗颅脑损伤的疗效。方法:以间接Meta分析的方法对已有研究进行合并,系统评价两种药物治疗颅脑损伤的GOS恢复良好率。结果:纳洛酮和GM1的GOS恢复良好率分别为69.15%和55.61%。结论:在治疗颅脑损伤的GOS恢复良好率方面,纳洛酮明显优于GM1。

Objective： To systematically evaluate the efficacy of curative effects of treating head injury between naloxone and GM1.Methods：GOS good recovery rate was taken as effectiveness indicator.An indirect Meta-analysis was developed.Results：The GOS good recovery rates are 69.15%and 55.61%for naloxone and GM1 respectively.Conclusion：The research showed that GOS good recov-ery rate in naloxone arm is better than that in GM 1 arm.