两种手术方式治疗乳腺癌的临床效果比较

Comparison of clinical efficacy and complications of two operation methods in the treatment of breast cancer

目的：比较改良根治术与保乳手术治疗乳腺癌的临床疗效及并发症发生情况。方法将110例乳腺癌患者按照就诊顺序随机分为两组，每组各55例，其中对照组采取改良根治术，观察组实施保乳手术，观察并比较两组临床疗效及并发症发生情况。结果观察组手术时间、术中出血量、切口长度和住院时间分别为（98．47±8．65）min、（82．59±4．86）mL、（4．80±0．87）cm和（8．66±1．77）d，均显著少于对照组的（156．52±10．23）min、（125．23±6．85）mL、（12．25±2．03）cm和（15．23±1．85）d（t＝8．12、7．58、9．88、8．72，均P＜0．05）；两组患者3年生存率、远处转移率及局部复发率差异均无统计学意义（χ2＝1．35、2．03、1．82，均P＞0．05）；观察组术后并发症发生率为3．63％，显著低于对照组的18．18％（χ2＝8．25，P＜0．05）。结论保乳手术治疗乳腺癌疗效显著，具有创伤小、恢复快、并发症少等优势，值得推广应用。

Objective To investigate the clinical effects and complications of modified radical mastectomy and breast conserving operation for breast cancer.Methods 110 cases of breast cancer were randomly divided into the two groups,55 patients in each group,the control group took the modified radical mastectomy,while breast conser-ving operation were carried out in observation group,the clinical efficacy and incidence of complications of two groups were observed and compared.Results The operation time,intraoperative blood loss,length of incision and hospitali-zation time of the observation group were （98.47 ±8.65）min,（82.59 ±4.86）mL,（4.80 ±0.87）cm and （8.66 ± 1.77）d,significantly less than （156.52 ±10.23） min,（125.23 ±6.85） mL,（12.25 ±2.03） cm and （15.23 ± 1.85）d in the control group （t=8.12,7.58,9.88,8.72,all P〈0.05）;3 years survival rate,the rate of distant me-tastasis and local recurrence rate of the two groups had no significant difference （χ^2=1.35,2.03,1.82,all P〉0.05）;The incidence of complications of the observation group was 3.63%,significantly lower than 18.18% of the control group （χ^2=8.25,P〈0.05）.Conclusion Breast conserving operation has a significant efficacy for breast cancer,with less trauma,quicker recovery,fewer complications,which is worthy of extensive promotion and application in clinical practice.