摘要
双侧肾母细胞瘤有同时发生和异时发生两种表现形式,同时性双侧肾母细胞瘤的发生率明显高于异时性。本文主要介绍同时性双侧肾母细胞瘤。根据多个文献报道,在肾母细胞瘤中,同时性双侧肾母细胞瘤发生率约为3.6%~8%。其中Hamilton等在3335例肾母细胞瘤中检出188例双侧肾母细胞瘤,后者发病率占全部肾母细胞瘤的5.6%。双侧肾母细胞瘤起病较早,发病年龄中位数为2.3岁,明显低于单侧肾母细胞瘤3.9岁的中位数年龄。双侧肾母细胞瘤组织学预后不良型较单侧多见,约为10%。双侧肾母细胞瘤合并畸形的发生率较高,常见的有睾丸下降不全、尿道下裂和输尿管重复畸形等。因此,双侧肾母细胞瘤的治疗具有较高的挑战性。其理想的治疗结果是,既保证较高的治愈率,又维持正常的肾功能,防止发生终末期肾功能衰竭。现就其诊治进展综述如下。
出处
《临床小儿外科杂志》
CAS
2014年第5期452-455,共4页
Journal of Clinical Pediatric Surgery
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