碎裂QRS波与恶性室性心律失常患者的研究

Association between fragmented QRS wave and outcomes in patients with malignant ventricular arrhythmia

目的探讨急性心肌梗死(AMI)碎裂QRS波和扩张型心肌病(DCM)碎裂QRS波与恶性室性心律失常患者的预后。方法将70例AMI碎裂QRS波室性心律失常患者作为AMI组,35例DCM碎裂QRS波室性心律失常患者作为DCM组,均接受电除颤、电复律、置入型心律转复除颤器及相关药物治疗,并进行对比分析。结果 AMI组与DCM组接受治疗后24h存活率(91.42%vs 94.28%)、2周内存活率(81.42%vs 88.57%)、1年内存活率(72.85%vs 82.85%)比较,差异有统计学意义(P<0.05)。2组共11例接受置入型心律转复除颤器后,1年内均存活。结论碎裂QRS波与恶性室性心律失常有关,此类患者采用电除颤和电复律、置入型心律转复除颤器及相关药物治疗,能改善预后,降低病死率。

Objective To study the association of fragmented QRS wave of aute myocardial infarction （AMI） and dilated cardiomyopathy （DCM） with outcomes in patients with malignant ventricular arrhythmia.Methods Seventy ventricular arrhythmia patients with fragmented QRS wave of AMI served as an AMI group and 35 ventricular arrhythmia patients with fragmented QRS wave of DCM served as a DCM group in this study.The outcomes in these patients after they underwent electricl defibrillation,electroconversion,cardioverter defibrillator implantation,and drug treatment were comparatively analyzed.Results The 24 h,2-week and 1 year survival rates were significantly lower in DCM group than in AMI group after treatment （91.42％ vs 94.28％,81.42％ vs 88.57％,72.85％ vs 82.85 ％,P＜0.05）.A total of 11 patients in 2 groups who underwent cardioverter defibrillation survived within 1 year.Conclusion Fragmented QRS wave is associated with malignant ventricular arrhythmia.Electricl defibrillation,electroconversion,cardioverter defibrillator implantation and drug treatment can improve the outcomes and mortatility in patients with malignant ventricular arrhythmia.