乌附麻辛桂姜汤加减治疗非特异性下腰痛的临床疗效观察

Observation on Clinical Effect of Modified Wu-Fu Ma-Xin Gui-Jiang Decoction for Treatment of Nonspecific Low Back Pain

目的:观察乌附麻辛桂姜汤治疗非特异性下腰痛患者的临床疗效。方法:选取60例非特异性下腰痛患者,将其随机分为治疗组和对照组,各30例,治疗组予以乌附麻辛桂姜汤加减,对照组则口服尼美舒利缓释片常规治疗,均以7天为1个疗程,比较两组患者在疗程前后视觉模拟疼痛量表(VAS)、临床症状和体征的变化。结果:与治疗前相比,两组患者腰痛均缓解,VAS评分均明显改善(P<0.05),但治疗组和对照组比较,差异无统计学意义;治疗组急性腰痛患者的疼痛VAS评分改善比慢性腰痛患者更明显(P<0.05),对照组急慢性病种对比差异无统计学意义。治疗组总有效率为93.33%,对照组总有效率73.33%,治疗组临床疗效比对照组更显著(P<0.05);治疗组和对照组中急慢性腰痛患者对比差异无统计学意义。治疗组的复发率明显低于对照组(P<0.05),其中治疗组中,慢性腰痛患者复发率更高(P<0.05),对照组中急慢性对比差异无统计学意义。结论:乌附麻辛桂姜汤加减方治疗非特异性下腰痛疗效确切,尤其改善急性期腰痛效果明显,且无毒副作用,复发率低,值得临床进一步研究和推广。

This study was aimed to observe clinical effect of Wu-Fu Ma-Xin Gui-Jiang（WFMXGJ） decoction treatment for patients with nonspecific low back pain. A total of 60 nonspecific low back pain cases were selected and randomly divided into the treatment group and the control group, with 30 cases in each group. Patients in the treatment group were treated with modified WFMXGJ decoction, while cases in the control group were given routine treatment of oral administration of nimesulide sustained-release tablets. Seven days were one treatment course. Comparison was made on Visual Analogue Scale/Score（VAS）, clinical symptoms and body signs before and after treatment between two groups. The results showed that compared with pretreatment, low back pain were relieved with obviously improved VAS among patients in both groups（P〈0.05）. However, there was no significant difference between the treatment group and the control group. In the treatment group, acute low back pain VAS was obviously improved than the chronic low back pain VAS（P〈0.05）. There was no statistical significance between the acute and chronic low back pain in the control group. In the treatment group, the total effective rate was 93.33%; and the control group was 73.33%. The clinical effect of treatment group was more significant than the control group（P〈0.05）. There was no statistical significance on acute and chronic low back pain in the treatment group and the control group. The recurrent rate of the treatment group was significantly lower than the control group（P〈0.05）. In the treatment group, the recurrence rate of chronic low back pain patients was higher（P〈0.05）. There was no significant difference on the comparison between acute and chronic low back pain in the control group. It was concluded that modified WFMXGJ decoction had obvious therapeutic effect on treatment of nonspecific low back pain, especially for the improvement of acute low back pain, with non-toxic side effects and low recurrence rate. It is worthy of further research and promotion