黄芪药材有效成分含量的相关性研究

Study on the Relevance of the Effective Components in Radix Astragali

目的:研究黄芪药材有效成分含量之间的相互关联性。方法:测定不同产地和年限的10批次黄芪中可能影响其内在质量的8种有效成分的含量,对测定数据进行PCA主成分和聚类分析以及SPSS关联性分析。结果:山西浑源样品质量较优且与其他产地黄芪样品可以明显区分,有效成分黄芪甲苷与总多糖、毛蕊异黄酮与总黄酮、芒柄花素与粗脂肪含量之间存在显著正相关。结论:黄芪多指标评价时可以用某一有效成分的多少来间接地反映出另一有效成分的优劣,从而探索出一种黄芪质控的新思路("一测多评")。

Objective ： To establish a new quality evaluation method for Radix Astragali and study relevance of the effective components. Methods ： 8 kinds of effective components in different origin and age of 10 batches of Radix Astragali were determined composition. All the dates were analyzed with PCA and SPSS. Results： The quality of Shanxi Hunyuan sample was betther than the other areas of RA samples and can be distinguished each other. There were a significant positive correlation between effective components of astragaloside and total polysaccharide, calycosin and total fIavonoids, formononetin and crude fat content. Conclusion： The method of multi - compo- nents quantitation by one marker has been verified in RA and it is to be a new quality evaluation pattern for RA.