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胎膜早破孕妇血清IL-6、CRP水平与宫内感染的关系 被引量:10

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摘要 目的研究白介素-6(IL-6)、c-反应蛋白(C-reactiveProtein,CRP)在胎膜早破(PROM)孕妇的血清、羊水中的含量,探讨其与胎膜早破及宫内感染的关系。方法选取我院2012年1月~2013年12月剖宫产分娩的足月胎膜早破孕妇30例作为实验组(PROM)组,同期因社会因素剖宫产分娩的正常孕妇30例作为对照组;采用酶联免疫吸附法(ELISA)测定孕妇血清及羊水中IL-6、CRP的水平,同时2组均取胎盘做病理检查。结果(1)PROM组孕妇血清及羊水中IL-6、CRP的含量均高于对照组(P〈0.05);(2)PROM组中,绒毛膜羊膜炎者21例,其血清、羊水中IL-6、CRP水平均高于非绒毛膜羊膜炎者(P〈0.05);(3)经治疗后血中IL-6、CRP的含量明显下降。结论孕妇血中IL-6、CRP水平均与PROM及宫内感染有关,在临床指导用药方面具有较高的价值,可以作为常规检查项目。
作者 王海燕
出处 《继续医学教育》 2014年第11期36-38,共3页 Continuing Medical Education
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参考文献9

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同被引文献74

  • 1郭文静.60例胎膜早破的临床观察和护理[J].中文科技期刊数据库(文摘版)医药卫生,2015(8):54-54. 被引量:1
  • 2徐芳,段生鸾,姚李香.早产病因237例分析[J].昆明医科大学学报,2012,33(4):89-92. 被引量:6
  • 3安晶慧,毛健.宫内感染与早产儿脑白质损伤发病机制研究[J].中国中西医结合儿科学,2006(2):65-66. 被引量:8
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  • 6肖秋风.胎膜早破孕妇血清IL-6水平与宫内感染的相关性研究[D].福建医科大学.2012.
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  • 8卞显凤.探讨C反应蛋白、白介素6与检测足月胎膜早破感染的关系[J].皖南医学院,2013,5:68-70.
  • 9靳钰,申彩霞,刘晓宇.IL-6、TNF-a、MMP-8与胎膜早破早产及宫内感染的关系[J].中国优生优育,2013,19(3):169-173.
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