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巨颌症的临床病理研究

A Study on the Clinicopathological Features of Cherubisms
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摘要 目的对巨颌症的临床病理特点进行研究分析。方法对1例巨颌症标本进行常规石蜡切片、HE染色、光镜观察。结果镜下见增生的纤维性组织代替了正常骨组织,纤维呈纵横交叉排列,多量多核巨细胞散在于纤维组织之间或围绕在血管周围。结论巨颌症是一种少见的良性病变,该病的诊断主要依靠组织病理学、临床表现及影像学检查。 Objective To study the clinicopathological features of cherubisms. Methods 1 case of cherubisms was studied by paraffin slices, HE staining and observed under microscopy. Results The fibrous tissues insteaded of the normal bone tissues. The fibrous tissues were horizontally crossing. Many multinucleated giant cells scattered in the fibrous tissues or around blood vessels. Conclusion Cherubism is a rare benign lesion. The diagnosis mainly depends on histopathology, clinical manifestation and imaging examination.
出处 《继续医学教育》 2014年第11期38-40,共3页 Continuing Medical Education
关键词 巨颌症 临床病理 Cherubism, Clinicopathology
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参考文献3

  • 1Papadaki ME, Lietman SA, Levine MA, et al.Chembism: Best clinical practice[J]. Orphanet J RareDis.,2012,7(S1):S6.
  • 2Tsodoulos S, Ilia A, Antoniades K, et al. Cherubism:a case report of a three-generation inheritance andliterature review[J]. J Oral Maxillofac Surg., 2014, 72(2):405, e1-9.
  • 3ZoharY, GrausbordR, ShabtaiF, et al. Fibrous dysplasiaand cherubism as an hereditary familial disease.Follow-up of four generations[J]. J CraniomaxillofacSurg, 1989, 17(8): 340-344.

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