极固宁^(TM)对活髓基牙牙髓组织影响研究

Influence of Green Or on the vital pulp after crown preparation

目的研究极固宁~TM对金属烤瓷全冠活髓基牙牙体预备后1、2周牙髓组织形态学的影响。方法选择2012年1月至2013年8月在福建医科大学附属口腔医院就诊患者15例,因正畸治疗需要而计划拔除40颗前磨牙(同一患者的同颌同名牙20对),将每对同颌同名牙随机分为对照组和试验组。对照组:金属烤瓷全冠牙体预备后直接用氧化锌丁香油水门汀黏固暂时冠;试验组:在牙预备体上涂布极固宁~TM后用氧化锌丁香油水门汀黏固暂时冠。分别于牙体预备后1、2周局麻下拔除同颌同名研究牙。常规组织病理切片,HE染色,显微镜下观察评价牙髓组织反应并测量颊侧髓角的剩余牙本质厚度。结果金属烤瓷全冠牙体预备后1、2周时,试验组与对照组的牙预备体颊侧髓角的剩余牙本质厚度差异均无统计学意义(P>0.05)。活髓基牙全冠牙体预备后1周,对照组的牙髓组织炎症反应比试验组严重(P<0.05);而牙体预备后2周,对照组与试验组的牙髓组织反应差异无统计学意义(P>0.05)。不论是金属烤瓷全冠牙体预备后1周或2周,所有样本均未见第三期牙本质的形成。结论极固宁~TM在金属烤瓷全冠牙体预备后1周时可降低活髓基牙牙髓组织的炎症反应。

Objective To study vital pulp response after 1 week and 2 weeks of Green Or applied to the surface of porcelain fused to matal crown（PFM）preparations.Methods From 2012 January to 2013 August,15 patients were selected in the Affiliated Stomatological Hospital,Fujian Medical University. Totally 40 biscuspids（20 pairs of human biscuspids,of which every 2 teeth were from the same patient and the same jaw）,scheduled to be extracted for the orthodontic reasons,were prepared for PFM. Every pair of teeth was divided into 2 groups. In the control group,the temporary crowns were cemented with zinc oxide eugenol. In the testing group,Green Or was applied on the surface of preparations before the temporary crowns were cemented with zinc oxide eugenol. At 1 week and 2 weeks all the teeth were extracted and prepared according to normal histologic techniques. Serial sections were stained with HE. The intensity of the pulp response was evaluated by light microscope. The remaining dentine thickness（RDT）was measured for each tooth specimen using a light microscope adapted to a video-camera.Results After the period of 1 week and 2 weeks,little difference of RDT was found in the control group and in the testing group（P〉 0.05）. After the period of 1 week of post-operation,the control group had more intense imflammatory cellular response than the testing group（P〈 0.05）. Whereas little difference of pulpal response was found in the control group and in the testing group after the period of 2 weeks（P〉 0.05）. After the period of 1 week and 2 weeks,none of the specimens showed tertiary dentine secretion.Conclusion Green Or relieves the intensity of the vital pulpal imflammatory response after 1 week of full crown preparation.