便秘与血脂异常患者临床初探

A preliminary exploration between constipation and blood lipid of patients

目的:分析不同人群的血脂情况,探讨便秘(慢性功能性)与血脂异常的关系。方法:观察组1为特定时期全部血脂正常合并便秘的健康体检者55例,对照组1为55例同时期血脂正常且无便秘的健康体检者(随机抽取);观察组2为该时期全部血脂异常合并便秘的神经内科老年住院患者84例,对照组2为同时期84例血脂异常且无便秘该科老年住院患者(随机抽取);随访观察组2的人群,针对便秘进行干预,2周后将便秘明显改善者作为观察组3,将无改善者作为对照组3。对所有研究对象进行血脂检测,将同组的对照组与观察组数据进行统计学分析。结果:对照组1和观察组1的血脂检验结果差异无统计学意义(P>0.05);对照组2和观察组2的检验结果差异有统计学意义(P<0.05);对照组3和观察组3的检验结果差异有统计学意义(P<0.05),而在未进行干预前两组患者的原始数据间,差异无统计学意义(P>0.05)。结论:在本项研究中血脂正常人群样本中便秘与血脂未发现具有相关性;在老年高脂人群样本中,便秘与血脂有相关性。通过改善排便,试图改善血脂异常,通过改善排便,试图强化自我血脂调控。

Objective To analyze data of blood lipid in different groups, and explore the relationship between constipation（chronic functional） and blood lipid. Methods： Observation group 1： All 55 patients with normal blood lipid and constipation inhealth examinations from 2010 to 2013. Control group 1： A random selection of another 55 patients with normal blood lipid and no con鄄stipation in the same population. Observation group 2： All 84 elder resident patients with dyslipidemia and constipation from 2010 to2013. Control group 2： A random selection of another 84 elder resident patients with dyslipidemia and no constipation in the same pop-ulation. After blood lipid tests of all,these data were compared in the same group. Then we had an intervention to Observation group 2on constipation. two weeks later,we had a comparison between 32 cases of 84 with obvious improvement of Constipation and 28 cases of84 with no improvement. Results： According to these data, there was no statistically significant difference between observation group 1and control group 1 （P〉0. 05）; the difference was statistically significant between observation group 2 and control group 2 （P〈0. 05）;The follow-up showed there was the statistical difference between 32 cases with obvious improvement of Constipation and 28 cases withno improvement of Constipation （P〈0. 05） . However ,the difference was not statistically significant （P〉0. 05） before intervention.Conclusions： In this study , when blood lipids was normal, no evidence showed that constipation had relation with blood lipid. In theolder population with dyslipidemia,constipation have some relation with blood lipid. By easing and smoothing defecation, we are tryingto reverse dyslipidemia . By doing, we are trying to strengthen self-management and regulation to blood lipid in daily life.