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BD方案与VAD方案治疗多发性骨髓瘤患者的临床观察 被引量:3

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摘要 目的:探讨硼替佐米联合地塞米松方案(BD方案)与长春瑞滨、吡喃阿霉素、地塞米松联合方案(VAD方案)治疗多发性骨髓瘤患者的临床观察。方法:选取76例多发性骨髓瘤患者,按数字表法随机分为两组,每组各38例,分别采用BD方案及VAD方案进行治疗。结果:BD方案组患者完全缓解(CR)23.68%、部分缓解(PR)31.58%、最小缓解(MR)28.95%、无变化(NC)10.53%、病情进展(PD)5.26%,总有效率84.21%,治疗疗效明显高于VAD方案组(P<0.05);两组患者治疗前各项指标无明显差异(P>0.05);两组患者治疗后各项指标相比,治疗前均有明显改善(P<0.05或P<0.01);BD方案组治疗后血红蛋白(112.1±17.3)g/L明显高于VAD方案组、β2-微球蛋白(2356.5±685.3)μg/L、M蛋白(21.4±7.6)×10-2、骨髓瘤细胞(12.6±4.4)×10-2,明显低于VAD方案组(P<0.05或P<0.01)。结论:多发性骨髓瘤采用BD方案治疗,安全、高效,疗效确切,值得临床推广。
作者 丁跃杰
出处 《中国民康医学》 2014年第24期81-82,共2页 Medical Journal of Chinese People’s Health
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