通里扶正汤促进大肠癌患者术后快速康复的临床研究

Clinical Study on Tongli Fuzheng Tang Promoting Postoperative Fast-track of Large Intestinal Carcinoma Pa- tients

为探讨通里扶正汤促进大肠癌患者术后快速康复的效果及其作用机制，将50例大肠癌术后患者随机分为治疗组和对照组，两组患者均按照快速康复外科理念治疗，在此基础上，治疗组经胃管给予通里扶正汤。观察两组患者术后首次肠呜音出现时间、肛门排气及排便时间，测定术前及术后免疫指标IgA、IgM和IgG含量。结果显示，（1）治疗组术后首次肠鸣音出现时间、肛门排气及排便时间均明显早于对照组，P＜0．05。（2）术后第7天，治疗组IgA、IgM和IgG含量均明显高于对照组，P＜0．05。结果表明，通里扶正汤能促进大肠癌患者术后胃肠功能的恢复，该作用可能是通过增强患者免疫功能实现的。

In order to explore the clinical effect and its mechanism of Tongli Fuzheng Tang（a Chinese med- icine formula,namely, purgative therapy and supporting vital qi decoction） in promoting postoperative fast- track of the patients with large intestinal carcinoma,author＇s department randomly divided the 50 patients with large intestinal carcinoma who had been received surgery into treatment group and control group, n=25,for each group; both groups were treated under the guidance of fast-track surgery concept, then treat- ment group was added with this decoction by gastric tube;after above treatment the time of the first-time rugitus sound appearing,the time of the first-time flatus from anus and bowel movement,as well as IgA, IgM and IgG levels before and after operation were recorded and detected in both groups.As results, 1）the time of first-time rugitus sound,flatus and bowel movement in treatment group were all significantly earli- er than that in controls（ P〈0.05） ;2）on the 7th day after operation IgA,IgM and IgG levels of treatment group were significantly higher than that of controls（ P〈0.05）.Results show that this decoction can pro- mote gastro-intestinal function recovery of large intestinal carcinoma patients after surgery which could be performed by strengthening patient＇s immune function.