颅内压增高患者高渗性脱水剂治疗分析

The Hypertonic Dehydration Treatment Analysis of Patients with Increased Intracranial Pressure

目的探讨高渗性脱水剂治疗颅内压增高症的临床疗效。方法选取30例颅内压增高症患者高渗性脱水剂患者临床治疗进行分析。结果高渗性脱水剂内起效时间10~35 min,用药后约30 min ICP降至最低点,降幅为7.5~12.5 mmHg,(1 mmHg=0.133 kpa),其有效降颅压时间为3.4 h^6.5 h。结论高渗性脱水剂通常要求快速输入才能达到有效作用,随着高渗物质的输入,脑组织渗透压也跟着逐渐提高,当停止输入后一段时间,脑渗透压可能会高于血渗透压,使水分子逆转由血人脑,颅内压回升。

Objective The clinical y hypertonic dehydration treatment effect of patients with increased intracranial pressure to be investigated. Methods Analyzing clinical y hypertonic dehydration treatment data selected from 30 cases of patients with increased intracranial pressure. Results The hypertonic dehydration wil be effective in 10 to 35 minutes,and the ICP would reduce to the minimum with the amount of 7.5-12.5 mmHg after the medicine is taken for about 30 minutes and the effective timing is from 3.4 to 6.5 hours.Conclusion The hypertonic dehydration is generally effective when it is injected rapidly,with the highly hypertonic matters importing,the brain tissue following an increase in osmotic pressure,while,once the input ceased,the brain osmotic pressure would probably be higher than blood osmotic pressure,and make the intracranial pressure rising caused by reversed flow of water molecules.