3270例呼吸道感染患儿非典型病原体结果分析

Analysis on the detection results of atypical pathogens in 3270 children with respiratory tract infection

目的分析本院呼吸道感染患儿非典型病原体现状和临床特征,为临床诊治提供依据。方法收集本院呼吸道感染的儿童患者3 270例,检测9种非典型呼吸道病原体的Ig M抗体,比较其阳性率与性别、年龄及季节的相关性。结果非典型呼吸道病原体的总阳性检出率为46.09%,以MP检出率最高;男童阳性率为45.45%,女童为46.63%,两者差异无统计学意义（P〉0.05）;冬季病原体检出率最高,秋季检出率最低,春季和夏季差异无统计学意义（P〉0.05）,与其他2季差异有统计学意义（P〈0.05）。0岁~1岁、~3岁、~6岁、~9岁和~14岁各年龄组间除了~3岁和~6岁组,差异有统计学意义（P〈0.05）。结论 MP是引起呼吸道感染最重要的非典型病原体,与性别无关,与年龄和季节有关,3岁~6岁儿童是易感人群。

Objective To acquire the present condition and clinical features of atypical pathogens in children infected with respiratory tract infections in our hospital and provide, evidence for clinical diagnosis and treatment. Methods Serum samples were collected from 3 270 children admitted into our hospital, and indirect immunofluorescence kits were used to test Immunoglobulin（IgM） antibodies against nine atypical pathogens in these serums, then the correlations between the positive rate and gender, season and age were compared. Results The total positive rate of nine atypical pathogens was 46.09% while mycoplasma pneumoniae（MP） was the most common pathogen. The positive rates for boy and girt were 45.45% and 46.63% respectively and no differences were found. As for season, the highest positive rate was found in winter, the lowest was autumn, and they differed from Spring and Summer （P 〈 0.05 ） while there were no differences between spring and summer （P 〉 0.05 ）. With regard to age, there were significant differences （P 〈 0.05） in all five groups except for - 3 y and - 6 y groups. Conclusion Mycoplasma pneumoniae is the main atypical pathogens leading to respiratory tract infections in children, and the infection of nine atypical pathogens is associated with age and season, but not gender. The susceptible population are children aged 3y-6y.