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血清NSE对妊娠高血压母分娩早产儿脑损伤的诊断价值 被引量:3

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摘要 目的探讨早产儿血清神经元特异性烯醇化酶(NSE)水平变化对判断妊娠高血压母分娩早产儿脑损伤的诊断价值。方法将本院2013年1月1日至2014年3月18日收治的96例妊娠高血压母分娩儿纳入实验组,于生后5-21天行颅脑MRI检查,依据颅脑MRI分为脑损伤组27例和无脑损伤组69例;选取同期健康母亲所生正常早产儿作为对照组18例。所有患儿均在其出生后第5天检测血清NSE浓度。结果妊娠高血压母分娩早产儿脑损伤组/无脑损伤组血清NSE值明显升高,和对照组比较有统计学意义(t1=6.67,t2=9.04,P〈0.05);脑损伤组血清NSE值较无脑损伤组有升高,但差异无统计学意义(t3=1.53,P〉0.05)。结论妊娠高血压母分娩早产儿NSE值升高,但和脑损伤程度不完全一致,外周血清NSE值可作为临床早期评价妊娠高血压母分娩早产儿脑损伤的参考指标。
出处 《齐齐哈尔医学院学报》 2014年第19期2858-2859,共2页 Journal of Qiqihar Medical University
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