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晚期卵巢癌新辅助化疗的研究进展 被引量：17

Progress in Neoadjuvant Chemotherapy in the Treatment for Advanced Ovarian Cancer
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摘要 卵巢癌是死亡率最高的妇科恶性肿瘤之一．约70％患者确诊时已属Ⅲ～Ⅳ期，预后较差。目前标准的治疗方式是理想初始肿瘤细胞减灭术，术后辅以铂类联合紫杉醇类化疗。对于病灶难以切除的晚期卵巢癌患者而言，可以选择术前新辅助化疗以提高满意减瘤术的手术机率。本文对晚期卵巢癌新辅助化疗的研究进展进行综述。 Ovarian cancer is one of the gynecological malignancies with the highest mortalityrate. Approximately 70% patients are diagnosed at advanced stages of the disease ,for which the prognosis is generally poor. Optimal primary debulking surgery （PDS） followed by platinum- based chemotherapy is the standard treatment. For advanced patients with unresectable lesions, neoadjuvant chemotherapy （NACT） is a way to improve the rate of cytoreductive surgery. This article reviews the progress in NACT in the treatment for advanced ovarian cancer.
作者 张颖 张英丽 张平
机构地区 浙江中医药大学第二临床学院 浙江省肿瘤医院
出处 《肿瘤学杂志》 CAS 2014年第11期942-946,共5页 Journal of Chinese Oncology
基金 浙江省自然科学基金(Y2111317)
关键词 新辅助化疗 卵巢肿瘤 细胞减灭术 neoadjuvant chemotherapy ovarian neoplasms primary debulking surgery
分类号 R737.31 [医药卫生—肿瘤]
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参考文献31

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二级参考文献18

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共引文献8

同被引文献132

引证文献17

二级引证文献110

肿瘤学杂志
2014年 第11期

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