脂肪量和肥胖相关基因对猪肉品质的影响及机制

Influence of Fat Mass and Obesity Associated Gene on Pork Quality and Its Mechanism

脂肪量和肥胖相关(fat mass and obesity associated,FTO)基因是最近发现的影响肉品质的一个重要候选基因。FTO基因在不同动物的各组织中分布广泛,该基因的多态性与肉品质性状等指标显著相关,并可能通过影响脂肪细胞的分化或发挥其去甲基化酶的功能,进而影响脂肪沉积。因此,深入研究FTO基因对猪肉品质的影响及其分子机制,将为今后改善猪肉品质提供新的研究思路。本文概述了FTO基因的发现、分布,FTO基因与肉质性状的关系以及其影响猪肉品质的可能作用机制。

The fat mass and obesity associated（ FTO） gene is a newly described candidate gene associated with meat quality. FTO gene can be detected in multiple tissues of different animals. The polymorphism of FTO gene is significantly associated with meat quality traits,and it may affect the fat cell differentiation or its demethylase function,thereby affecting the fat deposition. Study on the effects of FTO gene on pork quality and its molecular mechanisms can provide newstrategies for improving the pork quality. This reviewdescribed the discovery and distribution of FTO gene,the relationship between FTO gene and meat quality traits and its possible mechanism in influencing pork quality.