One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones

One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones

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摘要 A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol. A simple synthetic protocol has been developed involving the three-component reaction between 1,2-diamines, ethyl pyruvate and a-bromo ketones in the presence of Fe Cl3 as a catalyst. A number of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives were synthesized in excellent yields using this protocol.

作者 Mohammad Piltan

机构地区 Department of Chemistry

出处《Chinese Chemical Letters》 SCIE CAS CSCD 2014年第11期1507-1510,共4页 中国化学快报（英文版）

基金 Sanandaj Branch,Islamic Azad UniversityResearch Council for the financial support of this research

关键词 Pyrrolo[1 2-a]quinoxaline a-Bromo ketones 1 2-Diamines Ethyl pyruvate Pyrrolo[1,2-a]quinoxaline a-Bromo ketones 1,2-Diamines Ethyl pyruvate

分类号 O626.13 [理学—有机化学]

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参考文献7

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2Loghman Moradi,Mohammad Piltan,Hedieh Rostami,Golaleh Abasi.One-pot synthesis of pyrrolo[1,2-a]pyrazines via three component reaction of ethylenediamine,acetylenic esters and nitrostyrene derivatives[J].Chinese Chemical Letters,2013,24(8):740-742. 被引量：2
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二级参考文献3

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3Mohammad Piltan,Issa Yavari,Loghman Moradi.Tandem synthesis of functionalized hexaalkyl benzoisoquinolinopyrrolonaphthyridine-hexacarboxylate, via isoquinoline based multi-component reaction[J].Chinese Chemical Letters,2013,24(11):979-983. 被引量：5

共引文献1

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Chinese Chemical Letters

2014年第11期

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One-pot synthesis of pyrrolo[1,2-a]quinoxaline and pyrrolo[1,2-a]pyrazine derivatives via the three-component reaction of 1,2-diamines, ethyl pyruvate and α-bromo ketones

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二级参考文献3

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