无并发症白内障超声乳化术后黄斑厚度变化及其相关因素的研究进展

Macular thickness changes and its possible mechanism after phacoemulsification without surgical complications

白内障超声乳化联合人工晶状体植入术后患者黄斑厚度增加,这种厚度的增加可能与视力损害有关,但目前为止其机制仍不清楚.影响白内障超声乳化术后黄斑厚度变化的相关因素包括全身性因素（如糖尿病）、眼部因素（如高度近视）、手术因素（如超声乳化时间、黏弹剂等）及药物因素等.其发生的主要机制可能为炎性反应引起血-视网膜屏障破坏,导致黄斑厚度增加,针对其发生机制的药物可以预防及治疗亚临床黄斑水肿.

Macular thickness is increased in patients after phacoemulsification with intraocular lens implantation.The increase in macular thickness may lead to visual impairment.The mechanisms of macular thickness increase are still unknown.The relative factors that affect the macular thickness after cataract surgery include systemic factors,ocular factors,surgical factors and medical factors.Inflammation plays a major role in the mechanisms which causes the break drown of the blood-retinal barrier that leads to the increase in macular thickness.Medicine that focuses on its mechanisms may prevent SCME and treat SCME.