参麦注射液治疗气阴两虚型维持性血液透析患者的临床观察

Shenmai Injection Treating Sustainable Dialysis Patients of Both Deficiency of Qi and Yin

[目的]观察参麦注射液对慢性肾脏病(chronic kidney disease,CKD)-V期并伴有气阴两虚证候的维持性血液透析患者的临床疗效。[方法]选取2004年9月至2012年7月在本院透析符合气阴两虚证型诊断标准的患者共120例纳入本研究,随机抽取60例维持性血液透析患者为对照组,按常规透析方案治疗;另60例为治疗组,治疗组在对照组的基础上加用参麦注射液。两组疗程均为4周,4周后比较两组治疗前后气阴两虚证候积分评分、血压及血红蛋白等指标。[结果]治疗组治疗后的气阴两虚证候积分较治疗前有明显减少,透前透后收缩压、透后舒张压较治疗前有明显提高,血红蛋白升高,差异有统计学意义(P<0.05)。对照组治疗前后各指标均无明显差异(P>0.05)。治疗组与对照组比较,在治疗后,患者透前收缩压较高,差异有统计学意义(P<0.05)。[结论]参麦注射液能明显改善透析患者气阴两虚证候,提高透析中血压、血红蛋白,提高患者透析质量。

Objective]To observe the clinical effect of Shenmai Injection on chronic kidney disease（CKD） in V stage and the sustainable dialysis patients accompanied with both deficiency type of Qi and Yin.[Method] Choose 120 cases of such disease, randomly select 60 cases as control group with routine treatment;make another 60 cases as treatment group, added with Shenmai Injection. Both were treated for 4w, after that, compare their syndrome integral and score of both deficiency of Qi and Yin, blood pressure and hemoglobin indexes. [Result] In treatment group, the syndrome integral was much less than before, the blood pressure was increased a lot, so did the hemoglobin, the difference had statistical meaning. But there＆#39;s no marked difference on control group. The comparison of them showed difference of statistical meaning. [Conclusion] Shenmai Injection can markedly relieve the syndrome of both deficiency of Qi and Yin, improve the blood pressure and hemoglobin in dialysis, and improve patients＆#39; dialysis quality.