苏氨酸发酵液菌体分离实验与探讨

Experiments and discussion on removal of bacteria from the threonine fermentation broth

苏氨酸生产中去除菌体一般用陶瓷膜,截留的菌体蛋白通过絮凝沉淀、板框过滤后干燥,直接作为廉价菌体蛋白销售,产品附加值低,且污水处理负担重,苏氨酸回收率低。本文通过小试和中试生产对碟片分离与陶瓷膜分离进行比较,结果表明采用碟片分离发酵液菌体生产成本低、洗水少、苏氨酸回收率高。

Bacteria are generally removed by ceramic membrane in the production of threonine. The intercepted bacteria protein was sold at low price after flocculation precipitation, plate frame filtration and drying resulting in low added value, low threonine recovery and difficulty in sewage treatment. The bacteria removal method of disc separation and ceramic membrane separation were compared in small and pilot-scale. The results showed that lower cost and higher threonine recovery were obtained by using disc separation and the amount of washing water could be reduced.