摘要
目的:探讨加味金芙膏外敷对甘露醇所致静脉炎的防治效果。方法将家兔13只随机分为A组6只,B组7只。用20%甘露醇2.5 ml/kg静脉输注制作动物模型。左右耳自身对照,观察加味金芙膏外敷对甘露醇所致静脉炎发生的预防措施作用,以及加味金芙膏外敷对静脉炎的治疗作用。实验结果采用INS标准进行评分,实验结束后取耳进行组织病理学观察。结果预先给予加味金芙膏能明显降低INS分值,改善甘露醇注射所致的静脉炎症性病理改变,与模型组比较差异显著( P<0.05)。对于已经发生的静脉炎,加味金芙膏也有明显的治疗作用( P<0.01)。结论外敷加味金芙膏能可有效防治甘露醇所致静脉炎。
Objective To observe the preventive effect of Jiawei gold Fugao applying on phlebitis of rabbit ear margin caused by mannitol.Methods Totaled of 13 rabbits were randomly divided into A group with 6 rabbits and B group with 7 rabbits.Animal model was made by 20%mannitol 2.5ml/kg intravenous infusion .The left ear and right ear was compared , the preventive and treatment effect of Jia-wei gold Fugao applying on phlebitis were observed .The experimental results were evaluated by INS criteria , after the experiment taking ear did histopathological observation.Results Pretreatment with Jiawei gold Fugao can significantly decrease the INS score , improve intravenous inflammatory pathological change , there was significant difference compared with model group ( P〈0.05 ) .For phlebitis happened alread-y, Jiawei gold Fugao also had obvious therapeutic effects ( P〈0.01 ) .Conclusions Jiawei gold Fugao can effectively prevent phlebitis caused by mannitol.
出处
《国际护理学杂志》
2014年第11期3250-3252,共3页
international journal of nursing
基金
南京市卫生局2011年立项课题,编号:YKK11071