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支气管肺发育不良患儿血清sRAGE检测的临床价值 被引量：2

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摘要 目的 :研究新生儿支气管肺发育不良(bronchopulmonary dysplasia,BPD)血清可溶性晚期糖基化终末产物受体(soluble Receptor for advanced glycation end products,sRAGE)检测的意义。方法:选取新生儿重症监护病房住院BPD患儿45例(轻、中、重组分别为10、16、19例),在病程的不同时期以ELISA法检测血清中sRAGE水平,同时选取匹配非BPD患儿作为对照组。结果:与对照组相比,BPD组血清sRAGE水平明显增高;BPD组中,sRAGE在轻、中、重组间差异也有显著性(F=149.97,P<0.01)。结论:血清sRAGE可作为BPD的诊断和病情轻重评估的敏感指标。
作者 胡剑 赵赛 杨丽娟 程怀平 俞敏 唐云 田兆方
机构地区 南京医科大学附属淮安第一医院新生儿科
出处 《南京医科大学学报（自然科学版）》 CAS CSCD 北大核心 2014年第10期1374-1375,1381,共3页 Journal of Nanjing Medical University(Natural Sciences)
基金 江苏省临床医学专项(BL2014063)
关键词 支气管肺发育不良 新生儿 糖基化终末产物受体
分类号 R725.6 [医药卫生—儿科]
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参考文献12

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二级参考文献15

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共引文献21

同被引文献29

引证文献2

二级引证文献13

南京医科大学学报（自然科学版）
2014年 第10期

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