痰热清注射液联合西药治疗病毒流感随机平行对照研究

Random Parallel Control Study of Tanreqing Injection combined with Western Medicine in the Treatment of Influenza Virus

[目的]观察痰热清注射液联合西药治疗病毒流感疗效。[方法]使用随机平行对照方法,将101例门诊患者按就诊顺序号抽签方法简单随机分为两组。对照组42例,常规治疗,抗感染、退热等对症处理。治疗组59例,痰热清注射液,20mL+5﹪葡萄糖,静滴,1次/d;西药治疗同对照组。连续治疗7d为1疗程。观测临床症状(发热、头痛、乏力、全身酸痛)消失时间、平均红细胞体积、平均红细胞、血红蛋白、平均红细胞血红蛋白浓度、红细胞体积分布宽度、总蛋白、白蛋白、球蛋白、总胆红素、直接胆红素、间接胆红素、谷丙转氨酶、谷氨酰转肽酶、尿素氮、肌酐、尿酸等、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效30例,有效23例,无效5例,总有效率91.33%。对照组,显效11例,有效15例,无效16例,总有效率61.90%。治疗组疗效优于对照组(P<0.05)。症状(发热、头痛、乏力、全身酸痛)消失时间治疗组优于对照组(P<0.05);血液指标(平均红细胞体积、平均红细胞血红蛋白量、平均红细胞血红蛋白浓度和红细胞体积分布宽度)两组均与正常参考值无显著性差异(P>0.05);肝肾功能指标(总蛋白、白蛋白、球蛋白、总胆红素、间接胆红素、谷丙转氨酶、谷氨酰转肽酶、尿素氮、肌酐、尿酸)两组均与正常参考值无显著性差异(P>0.05)。[结论]痰热清注射液联合西药治疗病毒流感,疗效满意,无副作用,值得推广。

[ Objective ] To observe the clinical efficacy of Tanreqing injection in the treatment of Influenza virus infection on the basis of western medicine treatment. [ Method ] One hundred patients with Influenza virus infection were randomly divided into two groups.Both groups were treated by routine western medicine.The treatment group was given Tanreqing Injection.clinical symptom recovery time, clinical efficacy and the changes of routine blood and liver function of the two groups were compared in the course of the treatment. [ Result ] In clinical observation, we found that various laboratory parameters and the clinical efficacy of the treatment group were much better than those of the control group. [ Conclusion ] Adding Tanreqing Injection in the treatment of Influenza virus infection can significantly improve chnical efficacy.