丹参注射液与参麦注射液联合西药治疗急性冠脉综合征随机平行对照研究

Salvia Miltiorrhiza Injection and Ginseng Injection in Combination with Western Medicine Treatment of Acute Coronary Syndrome Random Parallel Control Study

[目的]观察丹参注射液与参麦注射液联合西药治疗急性冠脉综合症疗效。[方法]使用随机平行对照方法,将118例住院患者按掷骰子法简单随机分为两组。对照组58例常规内科治疗,硝酸甘油持续泵入联合β受体阻滞剂、抗血小板药及调脂类药物;符合溶栓的溶栓。治疗组60例丹红注射液30mL＋5%葡萄糖（或0.9%氯化钠）250mL,1次/d,静滴;参麦注射液60mL＋5%葡萄糖（或0.9%氯化钠）150mL,血压低或伴有心律失常参麦注射液增至80-100mL,1次/d,静滴;5%葡萄糖（或0.9%氯化钠）250mL＋单硝酸异山梨酯20mg,1次/d,静滴;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、心绞痛、心电图、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效43例,有效14例,无效3例,总有效率95.00%。对照组显效31例,有效17例,无效10例,总有效率83.33%。治疗组疗效优于对照组（P〈0.05）。[结论]丹参注射液与参麦注射液联合西药治疗急性冠脉综合征效果显著,值得推广。

[ Objective ] To observe salvia miltiorrhiza injection and ginseng injection in combination with western medicine treatment of acute coronary syndrome （ acs ） . [ Methods ] Using random parallel control method, 118 cases of hospitalized patients were randomly divided into two groups according to roll the dice method. Control group of 58 cases of conventional medical treatment, nitroglycerin continuous pumping joint beta-blockers, antiplatelet drug and lipid drugs ; In accordance with thrombolysis for thrombolysis treatment. The treatment group of 60 cases of 30 ml Dan red injection＋250 m15 % glucose infusion （ or 0.9% sodium chloride infusion ）, 1/d, the static drop; 60 ml glucose infusion and injection＋150 m15 % （or 0.9% sodium chloride infusion ）, 1/d, the static drop; Low blood pressure or associated with arrhythmia and increased injection to 80 - 100 ml; M15%250 glucose infusion （ or 0.9% sodium chloride infusion ） ＋20 mg isosorbide mononitrate, 1/d, the static drop; Western medicine treatment with the control group.Continuous treatment of 14d to 1 course of treatment. Observation of clinical symptoms and adverse reactions. As a course treatment, judge curative effect. [ Results ] The treatment group 43 cases had marked effect, 14 cases effective, 3 had no effect, the total effective rate was 95.00%. Control group 31 cases had marked effect, 17 cases effective, 10 cases were invalid, the total effective rate was 83.33%. The treatment group curative effect is better than that of control group （ P〈0.05 ） . [ Conclusion ] Salvia mihiorrhiza injection and injection in combination with refs western medicine treatment of acute coronary syndrome （ acs ） effect is remarkable, is worth promoting.