内镜窄带成像技术在Barrett食管中应用的效果分析

Application of endoscopic narrow band imaging technology in Barrett esophagus

目的 分析Barrett食管（BE）患者的临床表现,探讨内镜窄带成像技术在BE中的应用价值.方法 选择经胃镜及病理确诊的BE患者55例,分析患者的临床表现;分别采用普通内镜模式及NBI模式观察鳞状上皮交界处的病变轮廓、BE黏膜像,并进行清晰度评分;对普通内镜及NBI下所观察到的改变最显著部位取活检行病理检查.结果 BE主要表现为食管反流症状,但同时有约1/3患者无明显症状;NBI模式下鳞状上皮交界处的病变轮廓、BE黏膜像清晰度评分明显优于普通内镜,差异具有统计学意义.结论 NBI指导下的靶向活检对BE的诊断及监测有重要意义.

Objective To analyze clinical manifestations of Barrett esophagus （BE） and to investigate the application value of narrow band imaging in BE.Methods The clinical manifestations of 55 BE patients who were diagnosed by endoscopic and pathologically were analyzed.The contour at the junction of squamous epithelium lesion and BE mucosa image were observed by common endoscopic mode and NBI mode,and took clarity score.Then take the most significant part of the biopsy observed in ordinary endoscopy and NBI for pathological examination.Results The main clinical manifestations of BE is esophageal reflux symptoms,but at the same time,there were approximately 1/3 of patients had no obvious symptom.The lesion contour of squamous epithelial junction and Mucosa image clarity score of BE in NBI significantly higher than those in the normal endoscopy,the differences were statistically significant.Conclusions Targeted biopsy under the guidance of NBI has important significance in diagnosis and monitoring of BE.